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Erectile Dysfunction (ED) Treatments: Tadalafil vs Cialis Compared

ED is one of the most common and also least discussed medical conditions suffered by men.

There are a variety of different causes for ED and a number of different erectile dysfunction treatments available, both medicinal and non-medicinal. One of the most iconic, however, is the ‘blue pill’ that was popularized by Viagra. But Viagra isn’t the only ED pill on the market, in fact — Cialis has gained in popularity over the years. And now, it’s available in a cheaper, generic form (Tadalafil).

What’s tadalafil?

Tadalafil is a drug used to treat Erectile Dysfunction (ED). It is a phosphodiesterase type 5 (PDE5) inhibitor. PDE5 inhibitors tackle ED by temporarily increasing the blood flow to your penis.

Tadalafil was developed initially by the biotechnology company ICOS, before being evolved and marketed globally by Lilly ICOS — sold under the brand name Cialis.

Read more about Tadalafil and how it works.

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Buy Tadalafil Tablets
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What is Cialis?

Cialis is the trade name for the drug tadalafil. It is sold in tablet form and is available in doses of 10 mg and 20 mg.

Click here to find out more about what Cialis is.

Cialis Tablets (10mg & 20mg)
Cialis Tablets (10mg & 20mg)
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What is Tadalafil?

Tadalafil is now available as an unbranded, version of the popular ED pill Cialis. It’s a lot cheaper than Cialis and just as effective. It’s recently become available in the UK thanks to its patent expiring. Like Cialis, Tadalafil is provided in a number of doses ranging from 2.5mg to 20mg tablets.

Why take Tadalafil/Cialis?

Tadalafil is one of the four PDE-5 inhibitors available via prescription on the UK market.

These four are:

  • Tadalafil: sold under the trade name Cialis and works for approximately 36 hours
  • Sildenafil: sold under the trade name Viagra and works for approximately 8 hours
  • Vardenafil: sold under the trade name Levitra and works for approximately 8 hours
  • Avanafil: sold under the trade name Spedra and works for approximately 8 hours

This means that Tadalafil (and therefore Cialis) has the longest lifespan of any of the drugs licensed in the UK to treat ED.

*It is recommended that if you have a cardiovascular disease then you should take Tadalafil/Cialis with caution.

Side effects of tadalafil

The NHS reports a number of side effects that are associated with PDE-5 inhibitors. These include:

  • Back pain
  • Blocked or runny nose
  • Flushing (redness)
  • Headaches and migraines
  • Indigestion
  • Muscle pain
  • Nausea (feeling sick)
  • Vision disturbances
  • Vomiting (being sick)

These side effects come as a result of tadalafil’s capacity to widen your blood vessels.

All of the side effects associated with taking tadalafil usually recede within a couple of hours of taking the drug.

Read more about Tadalafil side effects here.

How successful is tadalafil in treating ED?

Studies have shown the drug tadalafil and its trade name Cialis to have a success rate of 60-70% in treating ED. Tadalafil (generic Cialis), is just as effective.

Want to find out more? You can read reviews of Cialis, as well as tadalafil reviews by our customers

Where can I buy ED treatments?

These are prescription-only drugs, so you need to have a doctor’s appointment either offline or online in order to get your hands on Cialis or Tadalafil.

As long as you have a prescription, you are able to buy Tadalafil/Cialis via a high street chemist, from your GP, or from an online pharmacy.

Is there a non-prescription alternative to tackling ED?

There are a number of non-prescription methods of addressing ED, including Viagra Connect, and it is recommended that you give consideration to these alongside any medication you take.

These non-prescription methods include:

  • Changing your diet (reducing alcohol and fat consumption)
  • Counselling
  • Lowering your stress levels
  • Stopping Smoking
  • Vacuum Devices (Penis Pumps)

Tadalafil is a drug which is used to treat ED. It works by temporarily increasing the blood flow to your penis and is sold via prescription under the trade name Cialis.

Cialis, and its generic version Tadalafil, are currently the longest-working ED medications on the UK market.

While it has a success rate of 60-70%, it is recommended that you also consider non-medicinal methods of treating ED before taking Tadalafil or Cialis.

Read next our comparison of Viagra Connect vs Viagra.

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Related Erectile Dysfunction (ED) guides

  • Sildenafil vs. Viagra: Which Should You Choose?

    If you’re looking for a treatment for erectile dysfunction then you’re probably well aware of Viagra. And if you know about Viagra then you may also have heard of sildenafil. But how do they compare? Both are effective treatments for erectile dysfunction, with the same active ingredient. The only real difference is in the name. Sildenafil citrate (the active ingredient in Viagra) was originally developed to treat high blood pressure and angina pectoris. Despite showing little evidence of treating these conditions during testing, the pharmaceutical giant Pfizer serendipitously discovered the drug provided an unexpected oral therapy for erectile dysfunction. Nicknamed the little blue pill, Viagra changed the world as an FDA-approved ED treatment in 1998 as the first major erectile dysfunction treatment on the market. It’s one of the fastest-selling drugs in history, but has its era of treating erectile dysfunction come to an end? Until 2013, Pfizer Inc owned an exclusive UK patent on this popular ED medication. And in 2020, Pfizer’s remaining patents on viagra expired. Pfizer’s initial discovery opened a profound and global conversation about erectile dysfunction, but now this exclusive patent has come to an end — the race to replace viagra is on.
  • Where to buy Viagra safely

  • What Happens if a Woman Takes Viagra?

    Viagra is used to treat erectile dysfunction in men, but does it have any effect on women? Find out what happens if a woman takes Viagra.

About the author

Andy Boysan
Andy Boysan
Andy Boysan

Andy is a co-founder and the Superintendent Pharmacist and Director at The Independent Pharmacy.

About the reviewer

Daniel Hurley
Daniel Hurley
Daniel Hurley

Dan is an experienced pharmacist having spent time working in both primary and secondary care. He currently supports our clinical team by providing robust clinical governance review of our internal processes and information.

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